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Necrox-5 methanesulfonate
CAS No. 1383718-29-3
Necrox-5 methanesulfonate ( Necrosis inhibitor 5 )
产品货号. M11590 CAS No. 1383718-29-3
NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1847 | 有现货 |
|
| 10MG | ￥2657 | 有现货 |
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| 25MG | ￥4520 | 有现货 |
|
| 50MG | ￥6383 | 有现货 |
|
| 100MG | ￥9072 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Necrox-5 methanesulfonate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter.
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产品描述NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter; improves mitochondrial oxygen consumption, and suppresses mitochondrial Ca(2+) overload during reoxygenation in an in vitro rat heart HR model, reduces the ouabain- or histamine-induced increase in mitochondrial Ca(2+).
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同义词Necrosis inhibitor 5
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通路Apoptosis
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靶点Apoptosis
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受体Apoptosis
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number1383718-29-3
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分子量645.80
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分子式C27H39N3O9S3
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纯度>98% (HPLC)
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溶解度DMSO : 170 mg/mL 263.24 mM
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SMILESCS(=O)(=O)O.CS(=O)(=O)O.C1COCCC1CNC2=CC(=CC3=C2NC(=C3)C4=CC=CC=C4)CN5CCS(=O)(=O)CC5
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化学全称5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-7-amine, dimethanesulfonate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Thu VT, et al. Cardiovasc Res. 2012 May 1;94(2):342-50.
2. Li X, et al. Allergy. 2016 Feb;71(2):198-209.
3. Park JH, et al. Int J Oncol. 2017 Jan;50(1):185-192.
4. Thu VT, et al. Korean J Physiol Pharmacol. 2016 Mar;20(2):201-11.
2. Li X, et al. Allergy. 2016 Feb;71(2):198-209.
3. Park JH, et al. Int J Oncol. 2017 Jan;50(1):185-192.
4. Thu VT, et al. Korean J Physiol Pharmacol. 2016 Mar;20(2):201-11.
产品手册
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